"在照片中间的是我的爷爷和奶奶"英语怎么写?

In the middle of the picture is my grandmother and grandfather.

楼上的谓语应该用are in the middle of the picture are my grandfather and grandmother.

It's my grandpa and grandma that are in the middle of the photo.

In the middle of the picture are my grandmother and grandfather.

grandmother和grandfather都是单数! 所以要用is

应该是：
In the middle of the picture are my grandmum and grandpa.